![]() Dogs with rupture of the cranial cruciate ligament were admitted, if the rupture had been surgically repaired more than 1 y previously. The algetic gait reported by the owner had to be chronic and stable. The OA had to have been determined to be the cause of the clinical signs, including an algetic gait, by a complete orthopedic examination performed by an orthopedic surgeon (JD or NHB). All dogs had radiographic evidence of OA in 1 or more joints. The purpose of this study was to evaluate scientifically the health benefits of a powder of quality elk velvet antler, referred here to QEVA, by administering it at the manufacturer’s recommended dosage to a pool of client-owned dogs afflicted with OA.ĭogs weighing more than 20 kg and older than 18 mo were included in the study. These studies, combined with the knowledge that chondroitin sulfate is found in velvet antler, suggested that this material could be useful in the treatment of OA ( 11, 12). Observations from in vivo studies demonstrated an antiinflammatory effect of a peptide (pilose antler peptide) isolated from velvet antler in a rodent model of inflammation ( 9, 10). This traditional Chinese medicine is a nutritional supplement made from the inner core of elk antler in the velvet stage of growth. Elk velvet antler is a well-known Chinese materia medica, which has been used clinically in East Asia for thousands of years in the treatment of various diseases and as a tonic ( 9). ![]() Research has led to the development of a broad range of pharmaceutical approaches to alleviate clinical signs by acting on the degenerative process, the associated inflammatory process, or both ( 5– 8). Disturbance in the normal homeostasis of joint tissue between degradation and synthesis is involved in this degenerative process, visually characterized by articular surface erosion, bone sclerosis, and osteophyte production, leading to pain, joint stiffness, and muscular atrophy ( 1– 4). Osteoarthrosis (OA) is a painful musculoskeletal condition in dogs, often being secondary to structural abnormalities, such as hip or elbow dysplasia or ligament injury. L’administration de la poudre de bois de velours s’est avérée efficace pour améliorer l’état des chiens arthritiques. Les analyses sanguines n’ont révélé aucun changement clinique. Les 25 chiens qui ont reçu la poudre de bois de velours pendant 60 jours ont connu des améliorations similaires. ![]() Les 13 chiens ayant reçu le placebo n’ont pas montré d’amélioration significative ( P < 0,05) cependant, leur démarche, leurs performances lors d’activités quotidiennes et leur vitalité se sont améliorées considérablement après qu’ils eurent reçu de la poudre de bois de velours, cette conclusion repose sur les écarts de valeurs plus important que ceux observés chez les chiens ayant reçu le placebo. Des analyses sanguines complètes ont été faites au jour 0, après 30 jours de placebo ou 60 jours de poudre de bois de velours. Les performances et l’entrain dans les activités quotidiennes ont été évalués par les propriétaires. Les signes cliniques ont été évalués par un chirurgien orthopédiste. L’analyse de la démarche a été faite à l’aide d’une plate-forme. Vingt-cinq autres chiens ont reçu de la poudre de bois de velours pendant 60 jours. Trente chiens ont reçu un placebo pendant 30 jours et, par la suite, de la poudre de bois de velours pendant 60 jours. Une poudre faite à partir de bois de velours de cerf de qualité a été évaluée chez des chiens ayant de l’ostéoarthrose lors d’une étude clinique à double insu. Résumé - Évaluation clinique de l’utilisation d’une poudre faite à partir de bois de velours de cerf de bonne qualité dans le traitement d’ostéoarthrose chez le chien. Administration of QEVA was effective in alleviating the condition in arthritic dogs. No clinical changes were revealed on blood analyses. The 25 dogs on QEVA for 60 days showed similar improvements. On placebo, the 13 dogs did not show significant improvement ( P < 0.05) however, their gait, their performances in daily life activities, and their vitality were significantly improved on QEVA, based on changes in values exceeding those observed when placebo was administered. Gait analysis measured with a force plate, clinical signs assessed by an orthopedic surgeon, performances in daily life activities and vitality assessed by the owners, and complete blood analyses were obtained at days 0, after 30 days of placebo and/or 60 days of QEVA. Twenty-five other dogs received QEVA for 60 days. Thirteen dogs received a placebo for 30 days and then QEVA for 60 days. A powder of quality elk velvet antler (QEVA) was evaluated on client-owned dogs with osteoarthrosis (OA) in a clinical, double-blind, and placebo-controlled study.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |